One of the contagious diseases spread by mosquitoes, such as malaria, affects people all over the world. High temperature, shivering, arthralgia (joint pain), vomiting, and other symptoms are present along with it. Malaria is characterised by cyclical episodes of abrupt coldness, rigour, fever, and sweating. The severity depends on the kind, and Plasmodium falciparum is responsible for the most severe form, which requires prompt treatment. If not, it might result in death. Human malaria infections are brought on by four species of the Plasmodium parasite: P. falciparum, P. vivax, P. ovale, and P. malariae.
The parasites, also known as sporozoites in humans, move to the liver where they develop and release the merozoites. More than 90 nations now have the disease, and it is estimated that there are over 500 million clinical cases and around 2 million fatalities from malaria each year.